Nöroprotektif Etkili Bir Flavonoid: Nobiletin
نویسندگان
چکیده
منابع مشابه
Anti-dementia Activity of Nobiletin, a Citrus Flavonoid: A Review of Animal Studies
Alzheimer's disease (AD), the most common form of dementia among the elderly, is characterized by the progressive decline of cognitive function and has a detrimental impact worldwide. Despite intensive laboratory and clinical research over the last three decades, pharmacological options for the prevention and effective long-term treatment of AD are not currently available. Consequently, success...
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Despite its importance, the death rate of ovarian cancer has remained unchanged over the past five decades, demanding an improvement in prevention and treatment of this malignancy. With no known carcinogens, targeted prevention is currently unavailable, and efforts in early detection of this malignancy by screening biomarkers have failed. The inhibition of angiogenesis, also known as angiopreve...
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Nobiletin, a bioactive polymethoxylated flavone, has been described to possess a diversity of biological effects through its antioxidant and anti-inflammatory properties. Vasodilator-stimulated phosphoprotein (VASP) is a common substrate for cyclic AMP and cyclic GMP-regulated protein kinases [i.e., cyclic AMP-dependent protein kinase (PKA; also known as protein kinase A) and cyclic GMP-depende...
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Upregulatory Effects of Nobiletin, a Citrus Flavonoid with Anti-dementia Activity, on the Gene Expression of mAChR, ChAT, and CBP Junko Kimura1, Kosuke Shimizu1, Jiro Takito2, Kiyomitsu Nemoto3, Masakuni Degawa3, Akihito Yokosuka4, Yoshihiro Mimaki4, Naoto Oku1, Yasushi Ohizumi1,5 1 Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan 2 ...
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Katatonik şizofreni şizofreninin sık rastlanılmayan bir alt tipi olup; katalepsi veya stupor, istemli hareketlerde postür alma, aşırı negativizim, mutizm, manyerizm, ekolali ve ekopraksi gibi sterotipik hareketler şeklinde klinik belirtiler gösterir. Atipik antipsikotikler, benzodiazepinler, EKT ve NMDA antagonistlerinin katatonik şizofreninin tedavisinde etkili olduğu bildirilse de, halen kata...
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ژورنال
عنوان ژورنال: Harran Üniversitesi Veteriner Fakültesi Dergisi
سال: 2017
ISSN: 2146-717X
DOI: 10.31196/huvfd.325789